These side effects may include: Its not known what percentage of people in clinical trials developed dental or jaw-related side effects. Inflammation of the inner lining of the heart (endocarditis) due to an infection may also happen more often in people who take Prolia. What should I know about Prolia vs. Evenity? For a detailed breakdown of Prolia versus Xgeva, check out this article. Additionally, in Prolia-treated men with nonmetastatic prostate cancer receiving ADT, a greater incidence of cataracts was observed. you can take. Prolia can cause many serious side effects. But doing so can cause more bone breakdown and increase your risk for bone fractures. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. supplements If youre concerned about tingling while using Prolia, talk with your doctor. You should not receive Prolia if you are allergic to denosumab, or if you have: low levels of calcium in your blood (hypocalcemia); or; if you are pregnant. Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Copyright 1996-2023 Cerner Multum, Inc. You may be interested in learning how Prolia compares to the medication Fosamax. If your pain doesnt ease with OTC options, your doctor may suggest prescription pain medication. Do not use denosumab if you are pregnant. So be sure to talk with your doctor about any past or upcoming surgery before starting treatment with the drug. They also include any added costs of the drug being given by a healthcare professional. Throw away a prefilled syringe after one use, even if there is still medicine left inside. Is the ketogenic diet right for autoimmune conditions? We do not endorse non-Cleveland Clinic products or services. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. Do not share this medicine with others. Medication Guide. Use of the terms female and male in this article refers to sex assigned at birth. You can use the study as a second opinion to make health care decisions. Osteoporosis treatment: Medications can help - Mayo Clinic Theyll need to confirm that you arent pregnant. A healthcare provider will give you this injection in a hospital or clinic. RA is an autoimmune condition in which your immune system attacks your joints. Dosage of drugs is not considered in the study. The risk is real, but rare. Your side effects from Prolia may also vary depending on your gender. Although very rare, Prolia can cause serious dental problems and jaw-related side effects. But if you look at D3 supplements online, youll see that most commercial supplements have higher doses usually either 1,000, 2,000, 5,000 or 10,000 IU. Learn more about some of the side effects Prolia may cause. Find out why people need calcium, which foods provide it, and what happens if they consume. Common Your risk for infection with Prolia may be higher if you have a weakened immune system. People need calcium for bone health and other functions. It could harm the unborn baby or cause birth defects. This may help to protect healthy cells from damage. Mild side effects of Prolia that have been reported include: Mild side effects of many drugs may go away within a few days or a few weeks. Using Prolia for Bone Loss in People With Breast Cancer All information is observation-only. Nausea can sometimes be a symptom of severe constipation. Please see Prolia full Available for Android and iOS devices. Your doctor can help you decide which drug is better for your needs. Prolia: Side Effects, Alternatives, How It's Administered, Xgeva is another brand of denosumab that treats high calcium levels caused by cancer and prevents bone breaks. If you have questions about treatment options for osteopenia or arthritis, talk with your doctor. Prolia is a prescriptionmedicine used to treat bone loss in women who are at high risk for fracture receiving certain treatments for breast cancer that has not spread to other parts of the body. Instead, it belongs to a different group of medications called biologics. Stopping some drugs leads to withdrawal symptoms because your body is used to the drug and needs it for you to feel normal. You should not receive Prolia if you are allergic to denosumab, or if you WebTake calcium and vitamin D as directed by your doctor, usually 1000 milligrams of Its a prescription drug thats used to treat osteoporosis and other forms of bone loss. 2023 Healthline Media UK Ltd, Brighton, UK. If youre concerned about side effects with Prolia, talk with your doctor. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem. We study millions of patients and 5,000 more each day. All rights reserved. Osteoporosis You should also talk with them if you have any serious side effects during Prolia treatment. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. They can also suggest ways to relieve this side effect. You may need to have a dental exam before you begin treatment with Prolia. There are no known interactions with Prolia and other medications, supplements, or other products. But its believed that these side effects are rare. We avoid using tertiary references. No, Prolia isnt a bisphosphonate. It is advisable to take 2 capsules in the morning with food and 1 in the evening also with food. Your doctor can discuss with you how to manage side effects and whether youll need to stop taking Prolia due to side effects. These problems may include: Your risk for mouth-related side effects may be higher if you have problems with your teeth. Can diet help improve depression symptoms? They might also recommend physical therapy, massage therapy, or using a heating pad. With arthritis, you have pain and inflammation of your joints. Other side effects may continue for as long as you receive the medication, but they can often be relieved with other treatments. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Your dentist may have you use a chlorhexidine mouth rinse before and after surgery to reduce your risk for jaw-related side effects. Prolia is also available in a biosimilar form. With peripheral edema, fluid builds up in your body and causes swelling in your arms and lower legs. What should I know about Prolia vs. Zometa? This is because the drug may be harmful to a growing fetus. (2021). * Sex and gender exist on spectrums. The drug could cause your calcium level to drop too low. Calcium Supplements Tell your doctor if you become pregnant. Web You will receive Prolia 1 time every 6 months. If you notice any tooth or jaw pain, or sensitivity while using Prolia, talk with your doctor or dentist right away. Your doctor or another healthcare professional will inject Prolia under the skin in one of the following areas: Prolia doses are given as an injection by healthcare professionals once every 6 months. Like most drugs, Prolia may cause mild or serious side effects. Be sure to talk with your doctor about your health history before you take Prolia. Prolia comes as a solution thats given as an injection under your skin. Be sure to talk with your doctor about which medication is right for you. What should I know about Prolia vs. Boniva? Prolia is a prescription medicine used to treat osteoporosis in women after menopause who are at high risk for fracture or cannot use another osteoporosis medicine or other osteoporosis medicines did not work well. Tingling wasnt specifically reported as a side effect of Prolia in clinical trials. Results may vary. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Musculoskeletal pain from Prolia is mild or manageable for most people. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. In rare cases, dental and jaw-related side effects have been reported with Prolia treatment. After you stop taking Prolia, youre more likely to experience bone loss, and your risk of a vertebral fracture increases. Thyroid or parathyroid surgery. WebYou should take calcium and vitamin D as your doctor tells you to while you receive For more information about how Prolia and Zometa compare with each other, see this article. If you have osteoporosis or bone loss, your doctor may discuss Prolia as a treatment option. American Dental Association (ADA) recommendations say that tooth extractions are allowable if needed during Prolia treatment, if both you and your dentist agree. These effects are called interactions. Serious infections may occur during treatment with Prolia. Prolia may cause serious side effects. Learn how to increase or maintain bone density here. Brush and floss your teeth regularly while receiving this medication. Drug class: Miscellaneous bone resorption inhibitors. Prolia is also used to treat glucocorticoid-induced osteoporosis in men and women at high risk of bone fracture. How long will the side effects of Prolia last? And they want you to get the best care possible. Talk with your doctor about which other treatments are better choices for you. Prolia injections administered by a healthcare professional. Do not treat yourself. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs.) See your dentist regularly. The phase IV clinical study analyzes what interactions people who take Prolia and Calcium have. Some examples of these treatments include: Talk with your doctor about other drugs you may need to take with Prolia. Dietary calcium is considered safe, but too much calcium in the form of supplements might have some health risks. A severe jawbone problem called osteonecrosis has rarely been reported with Prolia. Kidney problems. This is called hypocalcemia. Learn more about the FRAX score and the treatment options for, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. WebDrug interactions are reported among people who take Prolia and Calcium. What do I need to be aware of if I need a tooth extraction while Im using Prolia? You may have questions about Prolia and your treatment plan. If youd like to know more about the differences and similarities of Prolia and Evenity, see this comparison. You might like to know how Prolia and the drug Evenity compare. The use of the eHealthMe site and its content is at your own risk. Specifically, its used to increase bone mass in: Osteopenia (low bone mass), and low bone mineral density (BMD) can occur with older age. So treatment with the drug requires you to take daily calcium and vitamin D supplements. Prolia improves bone mass and increases bone mineral density. Women going through menopause have a higher risk of developing osteoporosis. If you miss a dose of Prolia, you should receive your injection as soon as you can. A special MedGuide will be given to you before each treatment. They can suggest ways to help relieve these side effects. It may also be higher if you have dental work done while youre taking Prolia. You may need to stop using the medicine for a short time. Xgeva is another brand of denosumab used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone.
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